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The FDA has approved Gardasil and Gardasil 9 for use in females ages 9 through 26 for the prevention of HPV-caused cervical, vulvar, vaginal, and anal cancers; precancerous cervical, vulvar, vaginal, and anal lesions; and genital warts.Gardasil and Gardasil 9 are also approved for use in males for the prevention of HPV-caused anal cancer, precancerous anal lesions, and genital warts.FDA has information for patients about Gardasil 9 available at Blood Vaccines/Vaccines/Approved Products/UCM426460After a vaccine is licensed by the FDA, the Advisory Committee on Immunization Practices (ACIP), a group of 15 medical and public health experts that develops recommendations on how to use vaccines to control diseases in the United States, makes additional recommendations to the Secretary of the U. Department of Health and Human Services and the Director of the CDC on who should receive the vaccine, at what age, how often, the appropriate dose, and situations in which it should not be administered.Persistent infections with high-risk HPV types can lead to cell changes that, if untreated, may progress to cancer.High-risk HPV types cause approximately 5% of all cancers worldwide (11).HPV is easily passed between partners through sexual contact.HPV infections are more likely in those who have many sex partners or have sex with someone who has had many partners.

Individuals who have previously received Gardasil may be able to also receive Gardasil 9.

Because none of the currently available HPV vaccines protects against all HPV infections that cause cancer, it is important for vaccinated women to continue to undergo cervical cancer screening.

There could be some future changes in recommendations for vaccinated women.

Gardasil is approved for use in males ages 9 through 26, and Gardasil 9 is approved for use in males ages 9 through 15.

Cervarix is approved for use in females ages 9 through 25 for the prevention of HPV-caused cervical cancer.

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They can be spread by vaginal, anal, and oral sex (1).

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